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Failure of antibiotic treatment may be blamed incorrectly on the wrong choice of antibiotic, and the drug might be replaced with a potentially more toxic agent. This could be particularly dangerous when concern for the fetus prevents the doctor from giving high doses whilst treating a serious infection in the mother. In general, full adult doses should be used when treating infection in a pregnant woman. Similarly, the length of therapy should be dictated by the disease and not unduly influenced by the fact that the patient is pregnant.
Uk/. Accessed 22 January 2006. 57 Livingstone C. Lice and scabies. Pharm J 1998;260:204–6. 58 Burgess IF, Brown CM, Lee PN. Treatment of head louse infestation with dimeticone lotion: randomised controlled equivalence trial. BMJ 2005;330:1423–5. 59 Janssen-Cilag Ltd. Datasheet for mebendazole (Vermox) tablets. uk/. Accessed 22 January 2006. 60 Leach F. Management of threadworm infestation during pregnancy. Arch Dis Child 1990;65:399–40. BLUK112-Rubin October 9, 2007 11:17 CHAPTER 3 Antibiotics in pregnancy Tim Weller, Conor Jamieson Key points r There is little evidence regarding the safety of most antimicrobial therapy in pregnancy r Clinical experience indicates the safety of penicillins and cephalosporins r Serious infections in pregnancy should be treated aggressively Introduction The use of antimicrobial agents during pregnancy often needs to be considered as pregnant women are at the same risk of acquiring infectious diseases as anyone else.
Therapeutics in Pregnancy and Lactation. Oxford: Radcliffe; 2000. 30 Anonymous. Any place for depot triamcinolone in hay fever? Drug and Ther Bull 1999;37(3):17–18. 31 Schatz M, Pettiti D. Antihistamines and pregnancy. Ann Allerg Asthma Immunol 1997;78:157–9. 32 Einarson A, Bailey B, Jung G, et al. Prospective controlled study of hydroxyzine and cetirizine in pregnancy. Ann Allerg Asthma Immunol 1997;78:183–6. BLUK112-Rubin 34 October 9, 2007 11:54 Chapter 2 33 Rost van Tonningen M. Antiallergy drugs and desensitisation.