Metallopharmaceuticals II: Diagnosis and Therapy by Michael F. Tweedle, Krishan Kumar (auth.), Professor Michael

By Michael F. Tweedle, Krishan Kumar (auth.), Professor Michael J. Clarke, Professor Peter J. Sadler (eds.)

Inorganic compounds supply a lot scope for the layout of novel and healing brokers. The frequent use of paramagnetic steel complexes as potent distinction brokers for magentic resonsance imaging (e.g. Gd) demonstrates that the toxicity of metals should be finely managed through the approriate selection of ligands. The succcessful concentrating on of radioisotopes back is dependent upon ligand layout and steel oxidation country. Bismuth and gold complexes have lengthy been utilized in drugs yet only in the near past have advances been made in figuring out the molecular foundation in their mechanism of motion. New parts with medical power contain using polyoxometallates and fullerenes as antiviral brokers and vanadium complexes as insulin mimetics.

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Fahlvik AK, Holz E, Leander P et al. (1990) Invest Radiol 25:113; b) Fahlvik AK, Holz E, Schroder U, Klaveness I (1990) Invest Radiol 25:793 97. Widder DI, GreifWL, Widder KI (1987) AIR 148:399 98. Maas R, Spielman R, Bonacker M et al. (1991) Abstracts of SMRM Meeting at Berkeley, CA, p 505 99. Weissleder R, Stark DD, Engelstad BL (1989) AIR 152:167 100. White DL, Aicher KP, Aria T et al. (1992) Mag Res Med 24:14 101. Rogers 1M, Lewis j, losephon L (1992) Mag Res Imag 12:1161 102 Bengele HM, Palmacci S, Rogers I, lung CW, Crenshaw I, losephon L (1994) Mag Res Mag 12:433 103.

Ferrucci IT, Stark DD (1990) AIR 155:943 96. Fahlvik AK, Holz E, Leander P et al. (1990) Invest Radiol 25:113; b) Fahlvik AK, Holz E, Schroder U, Klaveness I (1990) Invest Radiol 25:793 97. Widder DI, GreifWL, Widder KI (1987) AIR 148:399 98. Maas R, Spielman R, Bonacker M et al. (1991) Abstracts of SMRM Meeting at Berkeley, CA, p 505 99. Weissleder R, Stark DD, Engelstad BL (1989) AIR 152:167 100. White DL, Aicher KP, Aria T et al. (1992) Mag Res Med 24:14 101. Rogers 1M, Lewis j, losephon L (1992) Mag Res Imag 12:1161 102 Bengele HM, Palmacci S, Rogers I, lung CW, Crenshaw I, losephon L (1994) Mag Res Mag 12:433 103.

Inflammation, Infection and Deep-Vein Thrombosis ............. 104 104 References . . . . . . . . . . . . . . . . . . . . . . . .

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