By Michael T. Mazur MD, Robert J. Kurman MD (auth.)
Diagnosis of Endometrial Biopsies and Curettings, 2d version, revised and now with colour illustrations, keeps the culture of its predecessor as being the concise and whole diagnostic advisor to the endometrial biopsy. A assessment from sleek Pathology touts it as being "extremely helpful for the training pathologist since it outlines standards for analysis, is helping in fixing diagnostic dilemmas, and clarifies arguable issues." The textual content is dependent to offer a logical method of formulating a pathologic analysis from the varied array of tissue obtained within the surgical pathology laboratory with an emphasis on differential analysis. greater than 220 illustrations supplement the textual content, with 70 of them in complete colour all through. every one bankruptcy contains a part on "Clinical Queries and Reporting", which summarizes the positive aspects that has to be mentioned within the ultimate pathology document. The authors are popular gynecologic pathologists, and this booklet is derived from their long-running brief direction awarded on the overseas Academy of Pathology.
From rave studies of the 1st edition:
"This pleasant and good written monograph stresses the sensible facets and customary difficulties in endometrial biopsy interpretation. The preface states that this dissertation makes a speciality of frequently refined microscopic findings neglected by way of most traditional texts yet usually current pathologists with major demanding situations in day-by-day perform. considerably, the authors reach their goal." Int J Gyn Path
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Extra info for Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach
Sample text
The Ki-67 proliferation index in villous trophoblast is high at the junction with the CT at the base of the villus but decreases progressively toward the tip (distal end) of the trophoblastic column. The Ki-67 proliferation index is zero at the junction of the column with the decidua of the basal plate and is zero in the implantation-type IT cells as they “drop off” the column and infiltrate the endomyometrium. The Ki-67 proliferation index is low (<5%) in chorionic type IT. The Ki-67 index in ST cells is zero, which is consistent with that of terminally differentiated cells.
Placental Polyps . . . . . . . . . . Placenta Accreta . . . . . . . . . Endometrium Associated with Ectopic Pregnancy . . . . . . . . . . . . . Clinical Queries and Reporting . . . . 35 35 37 39 41 43 44 46 48 53 54 57 58 59 61 62 62 63 Recognition of the features of gestational endometrium, trophoblast, and villi, as well as the pathologic changes in chorionic tissues, is an important part of endometrial biopsy interpretation. The presence of intrauterine products of conception generally excludes the diagnosis of ectopic pregnancy and can help explain other 34 pathologic states such as abnormal bleeding or chronic endometritis.
Occasionally, benign cervical contaminants become more complex and troublesome in biopsies. Endocervical glands with squamous metaplasia or microglandular hyperplasia yield complex patterns, but these elements are cytologically bland and usually blend into more typical cervical epithelium (Fig. 22). In questionable cases, continuity with endometrial surface epithelium may help to establish origin in the corpus. It is also helpful to look at the surrounding stroma and see if it is of endometrial or endocervical type.