100 Questions and Answers About Depression, Second Edition by Ava T. Albrecht, Charles Herrick

By Ava T. Albrecht, Charles Herrick

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These events can include marriage, the birth of a child, a job change or promotion, or a move to a new neighborhood or home. 9. What chemicals regulate emotions? What chemical imbalance occurs in depression? Literally thousands of different chemicals participate in brain function and fall into different groups based on their chemical structure, mechanism of action, psychotropic effects, from where they originally come, or disease process they are designed to treat. The chemicals affecting emotional states in the brain consist of three broad types of compounds: neurotransmitters, which are chemically derived from single amino acids, the core constituents of proteins; neuropeptides, small links of amino acids that together form a protein with psychoactive effects; and hormones, chemicals made in different regions throughout the body that are released into the bloodstream and have psychoactive effects.

Although there is a greater understanding in society about depression, stigmatization continues to exist, and there can be concern about what to share about the condition with your family and friends. The decision to share information about your diagnosis can be fraught with more worries as to how others will perceive you than, for example, if you had to inform them of an infectious disease, a heart condition, diabetes, or even cancer. As with any other illness, you have a right to your privacy in terms of disclosure.

8 million adults in the United States suffer from depression. Close to 25% of persons seeking medical treatment in their primary care doctor’s office suffer from depression. Not only does depression have a personal cost on individuals and their families, it has a significant cost on society. Because many people who are depressed do not seek treatment, the cost of untreated depression to society runs into tens of billions of dollars, in part because of decreased productivity at work and overuse of primary healthcare services.

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